Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design EED-Targeted PROTAC which are EED degrader-1 and PROTAC EED degrader-2 [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,517.00 | |
50 mg | 8-10 weeks | $ 2,388.00 | |
100 mg | 8-10 weeks | $ 3,785.00 |
Description | MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design EED-Targeted PROTAC which are EED degrader-1 and PROTAC EED degrader-2 [1]. |
In vitro | With 14 days treatment, MAK683-CH2CH2COOH inhibits Karpas422 cells with a GI 50 of 14 nM [1]. |
Molecular Weight | 448.45 |
Formula | C23H21FN6O3 |
CAS No. | 2639882-68-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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MAK683-CH2CH2COOH 2639882-68-9 Others MAK683 CH2CH2COOH MAK683CH2CH2COOH MAK-683-CH2CH2COOH inhibitor inhibit