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Search Results for " dravet "

7

Compounds

Cat No. Product Name Synonyms Targets
T7699 AZD7325 AZD-7325 P450 , GABA Receptor
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
TN7252 Olivetolic acid 2,4-Dihydroxy-6-pentylbenzoic acid Antibiotic
Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity.
T74689 Zorevunersen
Zorevunersen (STK-001), an antisense oligonucleotide, aims to elevate productive SCN1A mRNA levels, thereby enhancing Nav1.1 sodium channel protein expression. It is utilized in researching Dravet syndrome.
T80433 δ-Buthitoxin-Hj1a Sodium Channel
δ-Buthitoxin-Hj1a, a scorpion-venom peptide, functions as a potent agonist for the NaV1.1 channel, exhibiting an EC50 value of 17 nM. It can be employed in research pertaining to Dravet syndrome (DS) [1].
T80188 Hm1a Sodium Channel
Hm1a, a disulfide-rich spider-venom peptide and NaV1.1 activator, reestablishes the function of inhibitory interneurons in a Dravet syndrome (DS) mouse model [1].
T80432 δ-Buthitoxin-Hj2a Sodium Channel
δ-Buthitoxin-Hj2a, a potent scorpion-venom peptide, acts as a NaV1.1 agonist with an EC50 value of 32 nM and is employed in Dravet syndrome (DS) research [1].
T79399 E2730 GABA Receptor
E2730 is a selective and noncompetitive inhibitor of the gamma-aminobutyric acid (GABA) transporter 1 (GAT1) that exhibits oral availability as well as antiepileptic properties. Its inhibition of GAT1 is dependent on the...
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