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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22723 | Dihydrosphingosine | Others | |
Dihydrosphingosine is a Protein kinase C inhibitor. | |||
T13632 | D-Erythro-dihydrosphingosine | Dihydrosphingosine,Octadecasphinganine,C18-Dihydrosphingosine,D-erythro-Sphinganine | Phospholipase , Endogenous Metabolite |
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity. | |||
T27189 | DL-threo dihydrosphingosine | DL-Safingol,DTD,DL threo dihydrosphingosine | |
DL-threo dihydrosphingosine is a cell-permeable inhibitor of the extracellular signal-regulated kinase (ERK) signalling cassette in mammalian cells. DL-threo dihydrosphingosine is effective against both growth factor- an... | |||
T83978 | Safingol hydrochloride | SPC 100270 hydrochloride,L-threo-dihydrosphingosine hydrochloride | PI3K , PKC |
Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a specific inhibitor of protein kinase C. It induces autophagy in solid tumor cells and cancer cell death by inhibiting the PKC and PI3-kinase pathways... | |||
T39401 | Sphinganine 1-phosphate | D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate | |
Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiat... | |||
T37454 | C16 dihydro Ceramide (d18:0/16:0) | Ceramide (d18:0/16:0),Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,N-Palmitoyl Sphinganine | |
C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced m... | |||
T36833 | A6770 | ||
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P l... |