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Search Results for " desipramine "

5

Compounds

Cat No. Product Name Synonyms Targets
T60445 Desipramine
Desipramine is a tricyclic psychotic compound with antidepressant activity. Desipramine inhibits the norepinephrine reuptake receptor in the central nervous system and reduces the sleep-related loss of genioglossus activ...
T0991 Desipramine hydrochloride NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T15773 Lofepramine Gamanil,Amplit,Leo 640,Lopramine 5-HT Receptor , Norepinephrine
Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, ...
T69620 Demexiptiline
Demexiptiline is a tricyclic antidepressant used in France for the treatment of depression. It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine.
T36521 Alaproclate (hydrochloride)
Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s =...
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