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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6459 | Cyclosporine | Phosphatase | |
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. | |||
T0945 | Cyclosporin A | Cyclosporine A,Ciclosporin,Cyclosporine | Phosphatase , Antibiotic , Complement System |
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM). | |||
T9936 | ZX-J-19J | N-(2,3-Diphenyl-6-quinoxalinyl)octanamide | Others |
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil. | |||
T0679 | Ketoconazole | R-41400,Xolegel,(±)-Ketoconazol,Extina | NADPH-oxidase , P450 , Hydroxylase , Antifungal , Ras |
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent. | |||
T28080 | Mocravimod | KRP 203 free base,KRP-203,KRP203 | |
Mocravimod is an agonist of sphingosine 1-phosphate receptor type 1. Mocravimod ameliorates atherosclerosis in LDL-R-/- mice. KRP-203 attenuates rat autoimmune myocarditis. KRP-203 combined with cyclosporine prolonged gr... | |||
T70889 | Oxeclosporin | ||
Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes. | |||
T32020 | Gusperimus | Deoxyspergualin,15-Deoxyspergualin | |
Gusperimus was synthesized by chemical modification of spergualin and in combination with cyclosporine A to prevent diabetes in susceptible NOD mice. | |||
T34999 | UNIL-088 | UNIL 088 | |
UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapid... |