4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3028 | Tripterin | Celastrol,Tripterine | Apoptosis , Mitophagy , Proteasome , Autophagy |
Tripterin (Celastrol) is a natural product, a proteasome inhibitor that inhibits the pancreatic rennet-like activity of the 20S proteasome (IC50=2.5 μM). Tripterin has anti-inflammatory, anti-infectious, and immunomodula... | |||
T4S1050 | Pristimerin | Celastrol methyl ester | NF-κB , Antibacterial |
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell... | |||
T27174 | Dihydrocelastrol | DHCE. (-)-Triptohypol C,Triptohypol C | |
Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through casp... | |||
T36197 | CAY10747 | ||
CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex ... |