Search Result

Search Results for " csf1 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10894	CSF1R-IN-1		c-Fms
	CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.		c-Fms
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T64066	CSF1R-IN-3		c-Fms , CSF-1R
	CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing ef...		c-Fms , CSF-1R
T62190	CSF1R-IN-7
	CSF1R-IN-7 (Formula I) is a CSF-1R inhibitor that can be used to study Alzheimer's disease.
T62187	CSF1R-IN-6
	CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF1R-IN-6 is a potent inhibitor of CSF1R, which is expressed in macrophages and is dependent on the CSF-1/CSF-1R signalling pathway for survival and differentiation of macropha...
T62364	CSF1R-IN-5
	CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF1R-IN-5 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-5 has the potential to be used in the study of cancer diseases.
T72574	Axl/Mer/CSF1R-IN-1
	Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds) of less than 0.1 μM.
T79472	CSF1R-IN-17		c-Fms
	CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM. It is capable of inhibiting osteoclast differentiation [1].		c-Fms
T62557	CSF1R-IN-14
	CSF1R-IN-14, an isoindolinone derivative compound, is a potent inhibitor of CSF1R. CSF1R-IN-14 has potential for cancer disease research.
T62342	CSF1R-IN-4
	CSF1R-IN-4 is a potent inhibitor of CSF-1R. CSF1R-IN-4 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-4 has potential for the study of cancer diseases. EGFR-IN-40.
T61554	CSF1R-IN-13
	CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell...
T62318	CSF1R-IN-9
	CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).
T62313	CSF1R-IN-10
	CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).
T61893	CSF1R-IN-12
	CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.
T62390	CSF1R-IN-8
	CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).
T62925	FASN-IN-5
	FASN-IN-5 (example 11) is a FASN inhibitor that can be used in studies of TH17 or CSF1-mediated diseases or disorders (e.g. cancer, immune disorders, obesity).
T78603	Sotuletinib dihydrochloride	BLZ945 dihydrochloride	c-Fms
	Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM. It promotes apoptosis in tumor cells and significantly restricts...		c-Fms
T70444	Edicotinib HCl
	Edicotinib, also known as JNJ-40346527, is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. FMS tyrosine kinase inhibitor JNJ-40...

Compounds

Target: c-Fms, c-Met/HGFR, Src

CSF1R-IN-3

T64066

Synonym:

Target: c-Fms, CSF-1R

Sotuletinib dihydrochloride

T78603

Synonym: BLZ945 dihydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00327	M-CSF/CSF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th...
TMPY-00464	M-CSF/CSF1 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.
TMPK-01325	M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.26 kDa and the accession number is XP_045221641.1.
TMPK-00323	M-CSF/CSF1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of...
TMPJ-01218	M-CSF/CSF1 Protein, Rat, Recombinant	Rat	HEK293 Cells
	Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and different...
TMPK-00322	M-CSF/CSF1 Protein, Human, Recombinant (aa 33-190)	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant (aa 33-190) is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.5 kDa and the accession number is P09603-1.
TMPK-00324	M-CSF/CSF1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of...
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-05335	M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.8 kDa and the accession number is P09603-1.
TMPY-05181	M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-04229	M-CSF/CSF1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.9 kDa and the accession number is P09603-2.
TMPY-03537	M-CSF/CSF1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	M-CSF/CSF1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P07141-1.
TMPY-04704	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)	Cynomolgus,Rhesus	HEK293 Cells
	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.1 kDa and the accession number is XP_005542489.1.
TMPY-04705	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	M-CSF/CSF1 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.8 kDa and the accession number is XP_005542489.1.
TMPY-01037	CSF1R Protein (Met1-Glu512), Human, Recombinant (His)	Human	HEK293 Cells
	CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P07333-1.
TMPJ-01418	CSF1R Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPJ-01419	CSF1R Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-l...
TMPY-05045	CSF1R Protein, Human, Recombinant (Domain I&II&III, His)	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is P07333-1.
TMPY-04938	CSF1R Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	CSF1R Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPK-00414	M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 57.4 kDa and the accession number is P07333-1.
TMPH-00354	CSF1R Protein, Feline, Recombinant (His & SUMO)	Feline	E. coli
	CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 70.8 kDa and the accession number is P13369.
TMPY-00881	CSF1R Protein, Human, Recombinant	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 55.1 kDa and the accession number is P07333-1.
TMPY-05429	CSF1R Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.2 kDa and the accession number is P07333-1.
TMPY-05040	CSF1R Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	CSF1R Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is XP_001107711.3.
TMPY-04358	CSF1R Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CSF1R Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76 kDa and the accession number is P07333-1.
TMPY-05513	CSF1R Protein (Ala299-Glu512), Human, Recombinant (His)	Human	HEK293 Cells
	CSF1R Protein (Ala299-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P07333-1.
TMPY-03920	CSF1R Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	CSF1R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is D4ACA7.
TMPY-03734	CSF1R Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	CSF1R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.5 kDa and the accession number is D4ACA7.
TMPY-06384	CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.76 kDa and the accession number is P07333-1.
TMPK-00415	M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 57.4 kDa and the accession number is P07333-1.
TMPY-01833	CSF1R Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CSF1R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.8 kDa and the accession number is P09581.
TMPY-05264	CSF1R Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 81.5 kDa and the accession number is P07333-1.
TMPY-05436	CSF1R Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CSF1R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.9 kDa and the accession number is P09581.
TMPY-06389	CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 83.04 kDa and the accession number is P07333-1.
TMPK-00656	M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 56.3 kDa and the accession number is G7P8P1.
TMPY-05043	CSF1R Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	CSF1R Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.3 kDa and the accession number is XP_001107711.3.
TMPH-00546	Epstein-Barr virus (strain GD1) BARF1 Protein (His)	EBV	E. coli
	Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
TMPH-00547	Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)	EBV	E. coli
	Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro.
TMPJ-01003	STAT5B Protein, Human, Recombinant (His)	Human	E. coli
	Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differ...