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Search Results for " cfi "

Targets

9

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T22288 (1E)-CFI-400437 dihydrochloride CFI-400437 dihydrochloride PLK
(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.
T22289 CFI-402257 Kinesin
CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
T7384 Ocifisertib(CFI-400945 free base) PLK
CFI-400945 is an potent, selective and orally active inhibitor of polo-like kinase 4(PLK4; Ki value of 0.26 nM).
T30804 CFI-401870 CFI 401870
CFI-401870 is an orally bioavailable potent tyrosine threonine kinase (TTK) inhibitor.
T70940 CFI-400936
CFI-400936 is a potent and selective TTK inhibitor with potential anticancer activity. This potent inhibitor of TTK (IC50=3.6nM) demonstrated good activity in cell based assay and selectivity against a panel of human kin...
T30805 CFI-401980
CFI-401980 is a potent and selective, novel class of TTK inhibitor.
T22645 CFI-400945 Others
CFI-400945 is an orally active, potent, and selective inhibitor of polo-like kinase 4.
T63318 CFI-400437
CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.
T70938 SN00799639
SN00799639, also known as SN639, is a potent inhibitor of the motility and development of parasitic larvae of Haemonchus contortus, a blood-feeding parasitic nematode of major economic importance in ruminants. SN639 dis...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06976 CFI Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.75 kDa and the accession number is Q61129.
TMPH-03273 Complement factor I Protein, Rat, Recombinant (His & Myc) Rat Baculovirus Insect Cells
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3.
TMPK-01023 Complement factor I Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPK-00776 Complement factor I Protein, Human, Recombinant (His) Human HEK293 Cells
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPY-06206 Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His) HMPV HEK293 Cells
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is...
TMPY-06207 Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His) HMPV HEK293 Cells
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is...
TMPH-02844 Properdin Protein, Mouse, Recombinant (His) Mouse E. coli
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple...
TMPH-02845 Properdin Protein, Mouse, Recombinant (His & Myc) Mouse HEK293 Cells
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Comple...
TMPH-03038 Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) Naja kaouthia E. coli
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to fo...
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