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CFI-402257

Catalog No. T22289 CAS 1610759-22-2

CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

CFI-402257, CAS 1610759-22-2

Pack Size	Availability	Price/USD
1 mg	10-12 weeks	$ 115.00
5 mg	10-12 weeks	$ 496.00
10 mg	10-12 weeks	$ 611.00
25 mg	10-12 weeks	$ 976.00
50 mg	10-12 weeks	$ 1,463.00
100 mg	10-12 weeks	$ 2,629.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.

Molecular Weight	498.587
Formula	C28H30N6O3
CAS No.	1610759-22-2

Storage

store at low temperture

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 112.5mg/mL (225.6mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Chan CY, et al. CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119514119. 2. Mason JM, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3127-3132.

Related Products

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EMD534085 Monastrol S-trityl-L-Cysteine BAY1217389 Dimethylenastron CFI-402257 TC-Mps1-12 Betamethasone 17-benzoate

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CFI-402257 1610759-22-2 Cytoskeletal Signaling Kinesin CFI402257 CFI 402257 Inhibitor inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.