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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7791 | Iberdomide | CC-220 | Apoptosis , Ligand for E3 Ligase |
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay). | |||
T10703 | Mezigdomide | CC-92480 | Apoptosis , E1/E2/E3 Enzyme , Molecular Glues |
Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity. | |||
T63771 | CC-99282 | ||
CC-99282 is a potent, orally active CRBN E3 ligase modulator (CELMoD).CC-99282 acts in combination with CRBN to co-induce effective and targeted degradation of Ikaros and Aiolos.CC-99282 can be used to study non-Hodgkin'... |