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Cat No. | Product Name | Synonyms | Targets |
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T4674 | SB297006 | SB 297006 | CCR |
SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of ... | |||
T76928 | Bertilimumab | ||
Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1]. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01001 | CCL11 Protein, Human, Recombinant | Human | E. coli |
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of all... | |||
TMPY-02550 | Eotaxin/CCL11 Protein, Human, Recombinant (His) | Human | E. coli |
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kem... | |||
TMPY-05353 | CCL26 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),... |