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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9317 | TAK-041 | NBI-1065846 | GPR |
TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist. | |||
T1290 | Oxiconazole nitrate | Ro 13-8996 | Others , Antibiotic , Antifection , Antifungal |
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole... | |||
T8825 | Capmatinib 2HCl.H2O | INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O | c-Met/HGFR |
Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. | |||
T1963 | Capmatinib | NVP-INC280,INC-280,INCB28060 | Apoptosis , c-Met/HGFR |
Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. | |||
T8416 | Capmatinib xHCl | INCB28060,Capmatinib hydrochloride(free base),INC280 | c-Met/HGFR |
Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activit... | |||
T4260 | Capmatinib 2HCl | INC-280 2HCl,INCB28060 2HCl | c-Met/HGFR |
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-... | |||
T68166L | Traxanox TFA | Traxanox TFA(58712-69-9 Free base) | Others |
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition... | |||
T68166 | Traxanox | Others | |
Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti... | |||
T64045 | Antitubercular agent-20 | ||
Antitubercular agent-20 is an orally active antitubercular agent. agent-20 showed low cytotoxicity and good tolerability in BALB/c mice. | |||
TP1339 | OVA Peptide 323-339 | ||
OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which play an important role in the development and development of immediate hypersensitivity in BALB/c mice. | |||
TN4470 | Lyoniside | Antifection | |
Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potentia... | |||
T78000 | OVA Peptide (323-339) | ||
OVA Peptide (323-339) constitutes a T and B cell epitope derived from Ovalbumin (Ova), crucial for eliciting immediate hypersensitivity reactions in BALB/c mice. | |||
T63945 | Antitubercular agent-19 | ||
Antitubercular agent-19 is an antitubercular agent. antitubercular agent-19 showed good antitubercular effects against MTB H37Rv and MDR-MTB (MIC <0.016 μg/ml). antitubercular agent-19 showed low cytotoxicity and relativ... | |||
T38044 | Reveromycin B | ||
Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50 = 6 μg/ml) and exhibits pH-dependent antifungal activity against... | |||
T34278 | Redaporfin | F 2BMet,F2BMet,F-2BMet,LUZ11,LUZ 11,LUZ-11 | |
Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26... | |||
T61532 | Tubulin polymerization-IN-6 | ||
Tubulin polymerization-IN-6 (compound 5f) is a potent inhibitor of tubulin polymerization, with an IC50 of 1.09 μM. It not only inhibits cell migration and tube formation but also has anti-angiogenic properties. Addition... | |||
T68875 | Xylocydine | ||
Xylocydine is a novel Cdk inhibitor, which is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo. Xylocydine also strongly inhibits the activity of Cdk7 and Cdk9, in vitro as well as... | |||
T37423 | Reveromycin D | ||
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μ... | |||
T71382 | KRC-108 | ||
KRC-108 is a multiple kinase inhibitor. KRC-108 is a potent inhibitor of Ron, Flt3 and TrkA as well as c-Met. KRC-108 inhibited oncogenic c-Met M1250T and Y1230D more strongly than wild type c-Met. The anti-proliferative... | |||
T37008 | Reveromycin A | ||
Reveromycin A is the major component of a complex of spiroketal antibiotics isolated from Streptomyces sp. It inhibits the mitogenic activity of epidermal growth factor in Balb/MK cells (IC50 = 0.7 μg/ml), displays antip... |