5
7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6854 | GSK621 | Apoptosis , AMPK , Autophagy | |
GSK621 is a specific and potent AMPK activator. | |||
T69800 | T-3861174 | ||
T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation. | |||
T75128 | I-152 | ||
I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties [1]. | |||
T78077 | E235 | Others | |
E235, an activator of the transcription factor 4 (ATF4), enhances the integrated stress response (ISR) and DNA damage response, thereby reducing cell viability and exhibiting anti-proliferative effects useful in tumor re... | |||
T74844 | Antiproliferative agent-23 | ||
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein,... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03274 | ATF-4 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19. | |||
TMPH-01313 | EIF4G1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c... | |||
TMPH-02240 | TMEM119 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an... | |||
TMPH-01312 | EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) | Human | E. coli |
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c... | |||
TMPY-01769 | 4EBP1 Protein, Human, Recombinant (His) | Human | E. coli |
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip... | |||
TMPY-04461 | TRIB3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T... | |||
TMPY-04385 | ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ... |