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Search Results for " atf4 "

Targets

5

Compounds

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6854 GSK621 Apoptosis , AMPK , Autophagy
GSK621 is a specific and potent AMPK activator.
T69800 T-3861174
T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.
T75128 I-152
I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties [1].
T78077 E235 Others
E235, an activator of the transcription factor 4 (ATF4), enhances the integrated stress response (ISR) and DNA damage response, thereby reducing cell viability and exhibiting anti-proliferative effects useful in tumor re...
T74844 Antiproliferative agent-23
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein,...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03274 ATF-4 Protein, Rat, Recombinant (His & Myc) Rat E. coli
ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19.
TMPH-01313 EIF4G1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-02240 TMEM119 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an...
TMPH-01312 EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc) Human E. coli
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPY-01769 4EBP1 Protein, Human, Recombinant (His) Human E. coli
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPY-04461 TRIB3 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T...
TMPY-04385 ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ...
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