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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1501 | Rifabutin | LM-427,Ansamycin | HSP , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Rifabutin (LM-427) inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Rifabutin is a semisynthetic ansamycin... | |||
T6558 | KW-2478 | KW2478 | HSP |
KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM. | |||
T21351 | Maytansine | NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine | Microtubule Associated , Antibiotic |
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. | |||
T40883 | N-Demethylansamitocin P-3 | ||
N-Demethylansamitocin P-3, a derivative of Ansamitocin, an antitumor ansamycin antibiotic, can be synthesized through the action of Streptomyces minutiscleroticus IFO 13361. | |||
T24895 | Tolypomycin Y | NSC177383,NSC 177383,B-2847-Y,NSC-177383 | |
Tolypomycin Y is a naturally occurring ansamycin antibiotic. | |||
T36385 | Ansatrienin A | ||
Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM)... | |||
T36650 | Ansatrienin B | ||
Ansatrienin B is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis., In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 21 nM... |