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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6854 | GSK621 | Apoptosis , AMPK , Autophagy | |
GSK621 is a specific and potent AMPK activator. | |||
T75128 | I-152 | ||
I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties [1]. | |||
T69800 | T-3861174 | ||
T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation. | |||
T78077 | E235 | Others | |
E235, an activator of the transcription factor 4 (ATF4), enhances the integrated stress response (ISR) and DNA damage response, thereby reducing cell viability and exhibiting anti-proliferative effects useful in tumor re... | |||
T74844 | Antiproliferative agent-23 | ||
Antiproliferative agent-23, a microtubule-destabilizing agent (MDA), disrupts the tubulin-microtubule system, leading to apoptosis through a mitochondrion-dependent pathway. This involves downregulation of Bcl-2 protein,... |