Home Tools
Log in
Cart

Search Result

Search Results for " apap "

9

Compounds

Cat No. Product Name Synonyms Targets
T0065 Acetaminophen 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol COX , Endogenous Metabolite , Histone Acetyltransferase
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
T38206 3-Cysteinylacetaminophen (trifluoroacetate salt) APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)
3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic...
T34785 TAPAP 3-Tapap
TAPAP binds to thrombin and trypsin.
T7036 2,4'-Dihydroxybenzophenone Antioxidant
2,4'-Dihydroxybenzophenone can effectively protect C57BL/6J mice from APAP-induced hepatotoxicity. Its mechanisms might be associated with its Antioxidant activity.
TWS1977 Kamebakaurin Kamebakaurine NF-κB
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...
T82219 Heilaohuguosu F
Compound 6, known as Heilaohuguosu F, is a tetrahydrofuranolignan demonstrating weak hepatoprotective properties. It exhibits a mild protective effect against acetaminophen (APAP)-induced hepatotoxicity in HepG2 cells.
T82748 Celosin L
Celosin L, a triterpenoid saponin, demonstrates hepaprotective activity and exerts protective effects against APAP-induced hepatotoxicity in HepG2 cells [1].
T69218 PUMAi HCl
PUMAi is an inhibitor of p53 up-regulated modulator of apoptosis (PUMA), a BH3-only Bcl-2 family member, mitigating acetaminophen (APAP)-induced hepatocyte necrosis and liver injury.
T83051 Anti-inflammatory agent 61
Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells and mitigates APAP-induced inflammation in HepG2 cells [1].
TargetMol