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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1914 | K02288 | K 02288 | ALK , TGF-beta/Smad |
K 02288 is a novel small molecule inhibitor of ALK1/2/3/6. | |||
T1977 | Dorsomorphin | Compound C,BML-275 | AMPK , Autophagy , TGF-beta/Smad |
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor ... | |||
T35348 | LDN-193189 2HCl | LDN-193189 2HCl,DM-3189 2HCl | ALK , TGF-beta/Smad |
LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited ... | |||
T1942 | DMH-1 | DMH1 | ALK , Autophagy , TGF-beta/Smad |
DMH-1 is a potent and selective BMP inhibitor. | |||
T6146 | Dorsomorphin dihydrochloride | BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride | AMPK , Autophagy , TGF-beta/Smad |
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases. | |||
T6158 | LDN-193189 HCl | LDN193189 Hydrochloride | ALK |
LDN-193189 HCl (LDN193189 Hydrochloride) is a selective BMP type I receptor kinases inhibitor. | |||
T35896 | AZ 12799734 | AZ12799734 | ALK |
AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04367 | BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) | Human | Baculovirus Insect Cells |
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is O00238-1. | |||
TMPY-03362 | BMPRIB Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1. | |||
TMPY-04496 | BMPRIB Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
BMPRIB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.4 kDa and the accession number is B2RRZ4. |