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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8678 | Naphthazarin | 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ | Apoptosis |
Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter... | |||
T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T0739 | Guaifenesin | Glycerol guaiacolate,Guaiacol glyceryl ether,Guaiphenesin | Others |
Guaifenesin (Guaiphenesin) is an expectorant that also has some muscle relaxing action. It is used in many cough preparations. | |||
T71286 | Guaifenesin-d3 | ||
Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin by GC- or LC-MS. Guaifenesin is an expectorant. It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and e... | |||
T34326 | Ridaifen-B | RidaifenB | |
Ridaifen-B, a tamoxifen derivative, works by inducing independent autophagy of Bcl-2, without estrogen receptor involvement. | |||
T19710 | Ciglitazone | Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878 | Apoptosis , p38 MAPK , PPAR |
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelia... | |||
T75485 | Dehydrobruceine B | ||
Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing fa... | |||
T78716 | MKA031 | ||
MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM. It disrupts the MIF-aryl hydrocarbon receptor interacting protein (AIF) interaction, impe... |