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Cat No. | Product Name | Synonyms | Targets |
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T1768 | 7ACC2 | Mitochondrial Metabolism , Monocarboxylate transporter | |
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells. | |||
T62418 | HACC2-IN-1 | ||
hACC2-IN-1 is a potent inhibitor of acetyl coenzyme A carboxylase 2 (ACC2) with an IC50 value of 2.5 μM for hACC2. hACC2-IN-1 has potential for obesity studies. | |||
T7163 | PF-05175157 | Acetyl-CoA Carboxylase | |
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively | |||
T7184 | Firsocostat | ND-630,NDI-010976,GS-0976 | Acetyl-CoA Carboxylase |
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively) | |||
T3622 | CP-640186 hydrochloride | CP 640186 HCl | Acetyl-CoA Carboxylase |
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit... | |||
TQ0243 | ND-646 | Acetyl-CoA Carboxylase | |
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively) | |||
T1889 | CP-640186 | CP 640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | |||
T12062 | MK-4074 | Others | |
MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM). | |||
T61341 | A-908292 | ||
A-908292 is a highly potent and selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), displaying an impressive IC50 of 38 nM. This compound serves as a valuable tool in the investigation of fatty acid metabolism [1]. | |||
T40675 | CP-610431 | ||
CP-610431 is a reversible, ATP-uncompetitive inhibitor of acetyl-CoA carboxylase (ACC), exhibiting isozyme nonselectivity. It inhibits both ACC1 and ACC2 with IC50 values of approximately 50 nM. CP-610431 offers potentia... | |||
T63961 | ACC1/2-IN-1 | ||
ACC1/2-IN-1 is a potent inhibitor of ACC1/2 and acts on ACC1 (IC50: 98.06 nM) and ACC2 (IC50: 29.43 nM). ACC1/2-IN-1 can be used in cancer research. | |||
T61978 | ACC1/2-IN-2 | ||
ACC1/2-IN-2 (compound PF-3) is a potent inhibitor of ACC1/2 with IC50s of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 shows antiproliferation activity and has research value in cancer research. |
Cat No. | Product Name | Species | Expression System |
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TMPY-04936 | BCL2A1 Protein, Human, Recombinant (His) | Human | E. coli |
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in... |