a-485 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14073	A-485		Epigenetic Reader Domain , Histone Acetyltransferase
	A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).		Epigenetic Reader Domain , Histone Acetyltransferase
T8838	CCI-007		Apoptosis , Histone Methyltransferase
	CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485		Apoptosis , Histone Methyltransferase
T29536	AC 485	AC-485,AC485
	AC 485 is a biochemical.
T18993	Fluorescein di(β-D-galactopyranoside)	FDG	Others
	Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λem=535 nm, λex=485 nm).		Others
T40210	EIF4E-IN-3	eIF4E-IN-3
	eIF4E-IN-3 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e), exhibiting noteworthy potential for investigating eIF4e dependent diseases, particularly cancer research (WO2021003157A1, compound 48...
T37656	MIT-PZR
	MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo. 1.D...
T79758	BQZ-485		Apoptosis
	BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction. This disruption impedes vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus, triggering sub...		Apoptosis
T82811	BTC tetrapotassium
	Tetrapotassium BTC is a calcium indicator with low affinity (Kd approximately 7-26 µM) that offers favorable characteristics for cellular calcium imaging, such as extended excitation wavelengths (400/485 nm), minimal sen...
T41172	FAM-DEALA-Hyp-YIPD
	FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide (Kd= 180-560 nM). Can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity....
T41173	FAM-DEALAHypYIPMDDDFQLRSF
	FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluor...
T37091	Indo-1 (sodium salt)
	Indo-1 (sodium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission ...
T38370	CAY10731
	CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm...
T35880	Renin Fluorogenic Substrate
	The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleava...
T37090	Indo-1 (potassium salt)
	Indo-1 (potassium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emissi...
T63980	BODIPY FL prazosin
	BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist that acts on α1a-AR (Ki: 14.5 nM) and α1b-AR (Ki: 43.3 nM). BODIPY FL prazosin can be used for the study of subcellular localization differences in α1-adrenoce...
T35549	Elsinochrome A
	Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...