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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1587 | Exemestane | EXE,FCE 24304,PNU155971 | Aromatase |
Exemestane (EXE) is an Aromatase Inhibitor. The mechanism of action of exemestane is as an Aromatase Inhibitor. | |||
T5S0543 | Isocurcumenol | Apoptosis , Estrogen Receptor/ERR , Reductase | |
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT). | |||
T67901 | SRD5A1-IN-1 | Others | |
SRD5A1-IN-1 is an inhibitor of steroid 5α-reductase type 1 (SRD5A1, IC50 = 1.44 µM). SRD5A1-IN-1 lowers the production of dihydrotestosterone and shows a significant decrease in the SRD5A1 protein expression. | |||
T81662 | N-Nitrosodicyclohexylamine | NDCHA | Androgen Receptor |
N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in opposition to 5α-dihydrotestosterone and reducing AR protein levels [1... |