7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14001 | 11-Beta-hydroxyandrostenedione | NSC-17102,4-Androsten-11β-ol-3,17-dione | Endogenous Metabolite |
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme... | |||
T4277 | Osilodrostat | LCI699 | Glucocorticoid Receptor , Others , Hydroxylase |
Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM). | |||
T30741 | Carboetomidate | ||
Carboetomidate is an analog of etomidate and does not bind to 11β -hydroxylase with high affinity. | |||
T33370 | Metyrapol | SU 5236,SU-5236,SU5236 | |
Metyrapol is a competitive inhibitor of 11-deoxycorticosterone hydroxylation by 11β-hydroxylase. | |||
T28272 | Osilodrostat phosphate | LCI699 phosphate,LCI 699 phosphate,LCI-699 phosphate | |
Osilodrostat phosphate is a potent oral 11β-hydroxylase inhibitor. | |||
T36915 | 21-Deoxycortisol | ||
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital a... | |||
T36472 | Tetrahydro-11-deoxy Cortisol | ||
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cyto... |