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Search Results for " 11β-hydroxylase "

7

Compounds

Cat No. Product Name Synonyms Targets
T14001 11-Beta-hydroxyandrostenedione NSC-17102,4-Androsten-11β-ol-3,17-dione Endogenous Metabolite
11-Beta-hydroxyandrostenedione (NSC-17102) is a steroid mainly found in the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue), which is a 11β-hydroxysteroid dehydrogenase isozyme...
T4277 Osilodrostat LCI699 Glucocorticoid Receptor , Others , Hydroxylase
Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).
T30741 Carboetomidate
Carboetomidate is an analog of etomidate and does not bind to 11β -hydroxylase with high affinity.
T33370 Metyrapol SU 5236,SU-5236,SU5236
Metyrapol is a competitive inhibitor of 11-deoxycorticosterone hydroxylation by 11β-hydroxylase.
T28272 Osilodrostat phosphate LCI699 phosphate,LCI 699 phosphate,LCI-699 phosphate
Osilodrostat phosphate is a potent oral 11β-hydroxylase inhibitor.
T36915 21-Deoxycortisol
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital a...
T36472 Tetrahydro-11-deoxy Cortisol
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11β-hydroxylase deficiency, a condition resulting from mutations in the cyto...
TargetMol