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Solid Tumors Target Proteins

Certain research progress has been made in CAR-T in solid tumors, including esophageal cancer, gastric cancer, liver cancer, colorectal cancer, pancreatic cancer, and bile duct cancer. Compared with hematoma, there are many types of solid tumor, various pathogenic mechanisms, difficult target selection, and more scattered targets in research projects. Overall, Mesothelin, HER2, EGFR, GPC3, GD2, CD276, MUC1 and Claudin 18.2 (CLDN18.2) were common targets.

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Species
Canine (7)
Cynomolgus (29)
Feline (1)
Human (149)
Mouse (32)
Rat (18)
Rhesus (12)
Rhesus Macaque (2)
Rhesus macaque (5)
Expression System
Baculovirus-Insect Cells (15)
CHO (1)
E. coli (2)
HEK293 (196)
Human Cells (29)
Tag
(2)
AVI (21)
C-6His (8)
C-6His-Avi (5)
C-Avi-6His (1)
C-Fc (9)
C-Fc-Avi (3)
C-His (11)
C-His-Avi (25)
C-hFc (5)
C-mFc (1)
GST (5)
His (96)
N-10His (1)
N-6His (1)
N-Fc (1)
N-His (4)
N-His-Avi (2)
N-hFc-Flag (2)
No Tag (1)
Tag Free (7)
hFc (52)
mFc (7)
rFc (1)
Cat No. product name / Synonyms Species Expression System
TMPJ-00648 EGFR vIII Protein, Human, Recombinant (His)
EGFR vIII Protein, Human, Recombinant (His)
Human Human Cells
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human...
TMPJ-00776 HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human Human Cells
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays ...
TMPJ-00777 HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
Human Human Cells
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays ...
TMPJ-00791 HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
Rat E. coli
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expre...
TMPJ-01231 Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)
Mouse Human Cells
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an...
TMPJ-01232 Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)
Mouse Human Cells
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an...
TMPJ-01423 GPC3 Protein, Rhesus macaque, Recombinant (His)
GPC3 Protein, Rhesus macaque, Recombinant (His)
Rhesus Macaque Human Cells
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate...
TMPJ-01432 CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
Human Human Cells
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epit...
TMPK-00078 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00079 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00080 CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Human HEK293
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TMPK-00105 NKG2D/CD314 Protein, Human, Recombinant (His & Avi)
NKG2D/CD314 Protein, Human, Recombinant (His & Avi)
Human HEK293
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
TMPK-00106 NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated
NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
TMPK-00107 NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled
Human HEK293
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
TMPK-00108 NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
Human HEK293
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
TMPK-00150 FOLR1 Protein, Human, Recombinant (His & Avi)
FOLR1 Protein, Human, Recombinant (His & Avi)
Human HEK293
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of fo...
TMPK-00205 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
Human HEK293
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
TMPK-00206 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
Human HEK293
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
TMPK-00207 EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
Human HEK293
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
TMPK-00283 CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)
CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)
Human HEK293
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to th...
EGFR vIII Protein, Human, Recombinant (His)
TMPJ-00648
The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human...
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00776
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays ...
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
TMPJ-00777
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays ...
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
TMPJ-00791
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expre...
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, hFc)
TMPJ-01231
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an...
Nectin-4 Protein, Mouse, Recombinant (aa 31-349, His)
TMPJ-01232
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains an...
GPC3 Protein, Rhesus macaque, Recombinant (His)
TMPJ-01423
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate...
CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
TMPJ-01432
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epit...
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
TMPK-00078
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His)
TMPK-00079
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00080
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
NKG2D/CD314 Protein, Human, Recombinant (His & Avi)
TMPK-00105
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00106
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled
TMPK-00107
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)
TMPK-00108
NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true ...
FOLR1 Protein, Human, Recombinant (His & Avi)
TMPK-00150
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of fo...
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
TMPK-00205
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
TMPK-00206
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
TMPK-00207
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2...
CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)
TMPK-00283
CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to th...
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TargetMol