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Enzyme-Linked Receptors

Enzyme-Linked Receptors are transmembrane receptors, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence an enzyme-linked receptor is an integral membrane protein possessing both catalytic, and receptor functions. Most enzyme-linked receptors are receptor tyrosine kinase.They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a catalytic function,and a single transmembrane helix. The signaling molecule binds to the receptor on the outside of the cell and causes a conformational change on the catalytic function located on the receptor inside the cell.

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Species
Canine (13)
Cynomolgus (34)
Human (231)
Mouse (89)
Rabbit (1)
Rat (40)
Rhesus (35)
Expression System
Baculovirus Insect Cells (33)
E. coli (3)
HEK293 Cells (396)
Tag
Avi (6)
C-6xHis (8)
C-6xHis-Avi (2)
C-Avi (2)
C-His (159)
C-His-Avi (48)
C-hFc (122)
C-hFc-6xHis (3)
C-hFc-Avi (2)
C-mFc (5)
C-mFc-Avi (4)
GST (27)
His (53)
N-His (5)
N-hFc (1)
Tag Free (18)
hFc (20)
Cat No. product name / Synonyms Species Expression System
TMPK-00499 HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
TMPK-00529 EPHA5 Protein, Cynomolgus, Recombinant (His)
EPHA5 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TMPK-00533 TYRO3 Protein, Cynomolgus, Recombinant (His)
TYRO3 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession...
TMPK-00563 EPHB2 Protein, Cynomolgus, Recombinant (His)
EPHB2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endoth...
TMPK-00566 ROR2 Protein, Cynomolgus, Recombinant (His)
ROR2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00572 ROR1 Protein, Canine, Recombinant (His)
ROR1 Protein, Canine, Recombinant (His)
Canine HEK293 Cells
ROR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.2 kDa and the accession numbe...
TMPK-00577 ROR2 Protein, Human, Recombinant (His & Avi)
ROR2 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00578 ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00579 ROR2 Protein, Human, Recombinant (hFc)
ROR2 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00686 FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a...
TMPK-00774 TrkA Protein, Human, Recombinant (aa 33-417, His)
TrkA Protein, Human, Recombinant (aa 33-417, His)
Human HEK293 Cells
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces recepto...
TMPK-00777 CD117 Protein, Mouse, Recombinant (His)
CD117 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
TMPK-00805 CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
TMPK-00847 FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc...
TMPK-00898 EphB3 Protein, Human, Recombinant (His)
EphB3 Protein, Human, Recombinant (His)
Human HEK293 Cells
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC comp...
TMPK-00899 EPHA5 Protein, Human, Recombinant (His)
EPHA5 Protein, Human, Recombinant (His)
Human HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TMPK-00901 TYRO3 Protein, Mouse, Recombinant (His)
TYRO3 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number ...
TMPK-00927 ALK Protein, Mouse, Recombinant (hFc)
ALK Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its gene...
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00976 AMHRII Protein, Human, Recombinant
AMHRII Protein, Human, Recombinant
Human HEK293 Cells
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian r...
HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
TMPK-00499
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
EPHA5 Protein, Cynomolgus, Recombinant (His)
TMPK-00529
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TYRO3 Protein, Cynomolgus, Recombinant (His)
TMPK-00533
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession...
EPHB2 Protein, Cynomolgus, Recombinant (His)
TMPK-00563
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endoth...
ROR2 Protein, Cynomolgus, Recombinant (His)
TMPK-00566
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR1 Protein, Canine, Recombinant (His)
TMPK-00572
ROR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.2 kDa and the accession numbe...
ROR2 Protein, Human, Recombinant (His & Avi)
TMPK-00577
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
TMPK-00578
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR2 Protein, Human, Recombinant (hFc)
TMPK-00579
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00686
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a...
TrkA Protein, Human, Recombinant (aa 33-417, His)
TMPK-00774
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces recepto...
CD117 Protein, Mouse, Recombinant (His)
TMPK-00777
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00805
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc...
EphB3 Protein, Human, Recombinant (His)
TMPK-00898
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC comp...
EPHA5 Protein, Human, Recombinant (His)
TMPK-00899
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TYRO3 Protein, Mouse, Recombinant (His)
TMPK-00901
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number ...
ALK Protein, Mouse, Recombinant (hFc)
TMPK-00927
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its gene...
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPK-00943
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
AMHRII Protein, Human, Recombinant
TMPK-00976
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian r...
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TargetMol