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Enzyme-Linked Receptors

Enzyme-Linked Receptors are transmembrane receptors, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence an enzyme-linked receptor is an integral membrane protein possessing both catalytic, and receptor functions. Most enzyme-linked receptors are receptor tyrosine kinase.They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a catalytic function,and a single transmembrane helix. The signaling molecule binds to the receptor on the outside of the cell and causes a conformational change on the catalytic function located on the receptor inside the cell.

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Species
Canine (13)
Cynomolgus (34)
Human (231)
Mouse (89)
Rabbit (1)
Rat (40)
Rhesus (35)
Expression System
Baculovirus Insect Cells (33)
E. coli (3)
HEK293 Cells (396)
Tag
Avi (6)
C-6xHis (8)
C-6xHis-Avi (2)
C-Avi (2)
C-His (159)
C-His-Avi (48)
C-hFc (122)
C-hFc-6xHis (3)
C-hFc-Avi (2)
C-mFc (5)
C-mFc-Avi (4)
GST (27)
His (53)
N-His (5)
N-hFc (1)
Tag Free (18)
hFc (20)
Cat No. product name / Synonyms Species Expression System
TMPJ-00642 TIE2 Protein, Human, Recombinant (hFc)
TIE2 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession numb...
TMPJ-00643 TIE2 Protein, Human, Recombinant (aa 23-745, His)
TIE2 Protein, Human, Recombinant (aa 23-745, His)
Human HEK293 Cells
TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the ...
TMPJ-00776 HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-...
TMPJ-00777 HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and t...
TMPJ-00791 HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
Rat E. coli
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expre...
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
Human HEK293 Cells
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the ac...
TMPJ-01017 Dtk Protein, Mouse, Recombinant (hFc)
Dtk Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number...
TMPJ-01018 Dtk Protein, Mouse, Recombinant (mFc)
Dtk Protein, Mouse, Recombinant (mFc)
Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number...
TMPJ-01081 Dtk Protein, Human, Recombinant (His)
Dtk Protein, Human, Recombinant (His)
Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracell...
TMPJ-01143 MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
Human HEK293 Cells
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibrone...
TMPJ-01158 ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc)
TGFBR1 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His)
FGFRL1 Protein, Human, Recombinant (His)
Human HEK293 Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00378 FGFR4 beta Protein, Human, Recombinant (His & Avi)
FGFR4 beta Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the...
TMPK-00379 FGFR4 Protein, Human, Recombinant (His & Avi)
FGFR4 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the acces...
TMPK-00380 FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26....
TIE2 Protein, Human, Recombinant (hFc)
TMPJ-00642
TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession numb...
TIE2 Protein, Human, Recombinant (aa 23-745, His)
TMPJ-00643
TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the ...
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00776
HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-...
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
TMPJ-00777
HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and t...
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
TMPJ-00791
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expre...
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
TMPJ-00899
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the ac...
Dtk Protein, Mouse, Recombinant (hFc)
TMPJ-01017
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number...
Dtk Protein, Mouse, Recombinant (mFc)
TMPJ-01018
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number...
Dtk Protein, Human, Recombinant (His)
TMPJ-01081
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracell...
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
TMPJ-01143
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibrone...
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
TMPJ-01158
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami...
TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ...
FGFRL1 Protein, Human, Recombinant (His)
TMPJ-01224
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi...
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00306
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TMPK-00328
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00329
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
FGFR4 beta Protein, Human, Recombinant (His & Avi)
TMPK-00378
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the...
FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the acces...
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00380
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26....
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TargetMol