Cytokines generally perform their biological functions by binding to the corresponding cytokine receptors on the cell surface. When a cytokine binds to its receptor, it initiates complex intracellular molecular interactions that ultimately lead to changes in cellular gene transcription. According to the structure of the cytokine receptor, it can be divided into different families or superfamilies, including immunoglobulin (Ig) superfamily, type I cytokine receptor, type II cytokine receptor, tumor necrosis factor receptor (TNFR) superfamily, and chemokine receptor.
Cat No. | product name / Synonyms | Species | Expression System |
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TMPK-00646 | Gp130/CD130/IL-6 R beta Protein, Rhesus macaque, Recombinant (His)
gp130/CD130/IL-6 R beta Protein, Rhesus macaque, Recombinant (His)
|
Rhesus macaque | HEK293 |
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inh... | |||
TMPK-00656 | M-CSF R/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)
M-CSF R/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also include... | |||
TMPK-00658 | IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protecti... | |||
TMPK-00686 | FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr... | |||
TMPK-00847 | FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00943 | PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th... | |||
TMPK-00986 | IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)
IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residu... | |||
TMPK-00987 | IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
|
Cynomolgus | HEK293 |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residu... | |||
TMPK-01050 | PDGF R beta/CD140b Protein, Canine, Recombinant (His)
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and... | |||
TMPK-01322 | FGFR4 Protein, Rhesus macaque, Recombinant (His)
FGFR4 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus macaque | HEK293 |
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that ... | |||
TMPK-01353 | IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellul... | |||
TMPK-01354 | IGF2R Protein, Human, Recombinant (His & Avi)
IGF2R Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellul... | |||
TMPK-01355 | IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellul... | |||
TMPK-01361 | IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellul... | |||
TMPY-00076 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)
IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that bel... | |||
TMPY-00135 | IL-6R Protein, Canine, Recombinant (His)
IL-6R Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-... | |||
TMPY-00257 | FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
FGFR3 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 |
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between membe... | |||
TMPY-00351 | FGFR2 Protein, Human, Recombinant (beta IIIc, His)
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
|
Human | HEK293 |
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho... | |||
TMPY-00385 | PDGFRB Protein, Rhesus, Recombinant (hFc)
PDGFRB Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-00387 | Gp130/IL6ST Protein, Human, Recombinant (hFc)
gp130/IL6ST Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. ... |