Cytokines generally perform their biological functions by binding to the corresponding cytokine receptors on the cell surface. When a cytokine binds to its receptor, it initiates complex intracellular molecular interactions that ultimately lead to changes in cellular gene transcription. According to the structure of the cytokine receptor, it can be divided into different families or superfamilies, including immunoglobulin (Ig) superfamily, type I cytokine receptor, type II cytokine receptor, tumor necrosis factor receptor (TNFR) superfamily, and chemokine receptor.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00395 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and patho... | |||
TMPK-00396 | FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00397 | FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00398 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00399 | FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00400 | FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00401 | FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00405 | IL-17R alpha/CD217 Protein, Human, Recombinant (hFc & Avi), Biotinylated
IL-17R alpha/CD217 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known ... | |||
TMPK-00412 | Gp130/CD130/IL-6 R beta Protein, Human, Recombinant (His)
gp130/CD130/IL-6 R beta Protein, Human, Recombinant (His)
|
Human | HEK293 |
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inh... | |||
TMPK-00414 | M-CSF R/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)
M-CSF R/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also include... | |||
TMPK-00415 | M-CSF R/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated
M-CSF R/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also include... | |||
TMPK-00419 | PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th... | |||
TMPK-00420 | PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th... | |||
TMPK-00421 | PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and... | |||
TMPK-00422 | PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and... | |||
TMPK-00455 | IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protecti... | |||
TMPK-00456 | IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protecti... | |||
TMPK-00475 | FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, t... | |||
TMPK-00481 | PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s... | |||
TMPK-00512 | IL-18 R1/CD218a Protein, Cynomolgus, Recombinant (His)
IL-18 R1/CD218a Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (I... |