The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. Most are multicyclic structures with oxygen-containing functional groups. About 60% of known natural products are terpenoids.
Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Ginkgo biloba, and the curcuminoids found in turmeric and mustard seed.
Many terpenes have biological activities and are used for the treatment of human diseases. The worldwide sales of terpene-based pharmaceuticals in 2002 were approximately US $12 billion. Among these pharmaceuticals, the anticancer drug Taxol and the antimalarial drug Artimesinin are two of the most renowned terpene-based drugs. All terpenoids are synthesized from two five-carbon building blocks. Based on the number of the building blocks, terpenoids are commonly classified as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and sesterterpenes (C25). These terpenoids display a wide range of biological activities against cancer, malaria, inflammation, and a variety of infectious diseases (viral and bacterial). In last two decades, natural-product bioprospecting from the marine environment has resulted in hundreds of terpenoids with novel structures and interesting bioactivities, with more to be discovered in the future. There is no doubt that more terpenoid-based clinical drugs will become available and will play a more significant role in human disease treatment in the near future.
Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
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T4S0675 | Polygalasaponin V | 162857-65-0 | 99.98% |
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Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia... | ||||
T3332 | Isosteviol | 27975-19-5 | 99.97% |
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Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ... | ||||
T3S1513 | (20R)-Protopanaxadiol | 7755-01-3 | 99.97% |
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1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial micr... | ||||
T4962 | Zingibroside R1 | 80930-74-1 | 99.96% |
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Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity. | ||||
T5739 | Paederosidic acid | 18842-98-3 | 99.96% |
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Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutam... | ||||
T4S1718 | Punicalin | 65995-64-4 | 99.95% |
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Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-depende... | ||||
T0687 | Simvastatin | 79902-63-9 | 99.95% |
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Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cho... | ||||
T3819 | Ursolic acid acetate | 7372-30-7 | 99.95% |
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Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO productio... | ||||
T3S0208 | Hederagenin 28-O-beta-D-glucopyranosyl ester | 53931-25-2 | 99.95% |
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Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage. | ||||
TN1059 | Ganoderic acid B | 81907-61-1 | 99.95% |
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Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards th... | ||||
T2829 | Isoalantolactone | 470-17-7 | 99.94% |
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Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells. | ||||
T5S1131 | Ganoderic acid C6 | 105742-76-5 | 99.92% |
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1. Ganoderic acid C6 has antinociceptive activity. | ||||
T2P2806 | Hederacolchiside A1 | 106577-39-3 | 99.92% |
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Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the paras... | ||||
T3917 | Protopanaxatriol | 1453-93-6 | 99.92% |
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Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist. | ||||
TN2296 | Vinaginsenoside R4 | 156009-80-2 | 99.92% |
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Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without ... | ||||
T5708 | LUPENONE | 1617-70-5 | 99.92% |
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Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhib... | ||||
T0433 | Artesunate | 88495-63-0 | 99.91% |
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Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and m... | ||||
TN1494 | Cimicifugoside H-1 | 163046-73-9 | 99.91% |
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Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. | ||||
T2808 | Bilobalide | 33570-04-6 | 99.91% |
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Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations. | ||||
T6S0619 | Pachymic acid | 29070-92-6 | 99.91% |
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Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways. |