The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. Most are multicyclic structures with oxygen-containing functional groups. About 60% of known natural products are terpenoids.
Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Ginkgo biloba, and the curcuminoids found in turmeric and mustard seed.
Many terpenes have biological activities and are used for the treatment of human diseases. The worldwide sales of terpene-based pharmaceuticals in 2002 were approximately US $12 billion. Among these pharmaceuticals, the anticancer drug Taxol and the antimalarial drug Artimesinin are two of the most renowned terpene-based drugs. All terpenoids are synthesized from two five-carbon building blocks. Based on the number of the building blocks, terpenoids are commonly classified as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and sesterterpenes (C25). These terpenoids display a wide range of biological activities against cancer, malaria, inflammation, and a variety of infectious diseases (viral and bacterial). In last two decades, natural-product bioprospecting from the marine environment has resulted in hundreds of terpenoids with novel structures and interesting bioactivities, with more to be discovered in the future. There is no doubt that more terpenoid-based clinical drugs will become available and will play a more significant role in human disease treatment in the near future.
Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TN3107 | 5-Deoxystrigol | 151716-18-6 | 98% |
|
5-Deoxystrigol is a highly active Striga germination stimulant. It has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a ... | ||||
T7920 | Geranylacetone | 3796-70-1 | 98% |
|
Geranylacetone has trypanostatic activity and could protect animals against the T. congolense-induced anaemia through the inhibition of sialidase and/or the prot... | ||||
T14192 | α-Amyrin acetate | 863-76-3 | 98% |
|
α-Amyrin acetate is a natural product( triterpeno), with anti-inflammatory activity, antispasmodic profile and the relaxant effect. | ||||
T2S0605 | Liquidambaric lactone | 185051-75-6 | 98% |
|
Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity. | ||||
TN1135 | Isoscabertopin | 439923-16-7 | 98% |
|
Isoscabertopin has anticancer activity. | ||||
T13797 | Nivalenol | 23282-20-4 | 98% |
|
Nivalenol is a fungal metabolite produced by Fusarium graminearum. Nivalenol induces cell death through caspase and intrinsic apoptotic pathways thus affecting t... | ||||
T8291 | 2-Carene | 4497-92-1 | 98% |
|
2-Carene is a naturally occurring bicyclic monoterpene found in many essential oils such as pine, cedar and cypress. It has been found to have anti-inflammatory,... | ||||
T8252 | Trans-Chrysanthemyl Alcohol | 5617-92-5 | 98% |
|
Trans-Chrysanthemyl Alcohol is a natural product. | ||||
T2S0287 | Araloside V | 340963-86-2 | 98% |
|
Araloside V (Congmunoside V) comes from the roots of Aralia elata. It can be used to treat neurasthenia. | ||||
TN1144 | Enmein | 3776-39-4 | 98% |
|
Enmein shows significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 microg/ml to 8.2 microg/ml | ||||
TN6528 | Butyrospermol | 472-28-6 | 98% |
|
Butyrospermol is a protolimonoid extracted from shea (Euphorbia). As a long-chain fatty acid ester first discovered from natural products, Butyrospermol has anti... | ||||
TN2243 | Sugiol | 511-05-7 | 98% |
|
Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and h... | ||||
TN4477 | Macrocarpal E | 142628-54-4 | 98% |
|
Macrocarpal E is a mesitylene diterpene diterpene derivative from Eucalyptus bluegum with antimicrobial activity. | ||||
TN3616 | Cedrelone | 1254-85-9 | 98% |
|
Cedrelone is a citrulline analog and a phenazine biosynthesis-like domain protein (PBLD) activator.Cedrelone induces apoptosis in cancer cells.Cedrelone is a ver... | ||||
TN3983 | Ergosta-7,22-dien-3-one | 32507-77-0 | 98% |
|
Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis.Ergosta-7,22-dien-3-one has pro-inflammatory propertie... | ||||
T75678 | Tomentosin | 33649-15-9 | 98% |
|
Tomentosin, a sesquiterpene lactone extracted from Caspian sea raspberry, has potential anti-inflammatory and anticancer activities, promoting apoptosis and inhi... | ||||
T8282 | (S)-(−)-Perillyl alcohol | 18457-55-1 | 98% |
|
(S)-(−)-Perillyl alcohol (Perillyl alcohol) , a monoterpene found in lavender, inhibits the farnesylation of Ras, upregulates the mannose-6-phosphate receptor an... | ||||
TN4918 | Roseoside | 54835-70-0 | 98% |
|
Roseoside ((6S,9R)-roseoside), a sesquiterpenoid isolated from Catharanthus roseus, has strong antioxidant and proinsulinic activity, inhibits lipid oxidation, e... | ||||
T38484 | Englerin A | 1094250-15-3 | 98% |
|
Englerin A, a TRPC4 and TRPC5 channel agonist, is a compound from the East African plant Phyllanthus engleri with analgesic, anti-inflammatory, and anticancer ac... | ||||
T8278 | (+)-Dehydroabietic acid | 1231-75-0 | 98% |
|
(+)-Dehydroabietic acid is a natural compound isolated from Rosin acid. |