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Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated
(Synonyms: RCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9) Copy Product InfoSynonyms: RCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9
Catalog No. TMPJ-00283 Copy Product Info
Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $213 | 7-10 days | 7-10 days | |
| 20 µg | $355 | 7-10 days | 7-10 days | |
| 50 µg | $625 | 7-10 days | 7-10 days | |
| 100 µg | $963 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Biotinylated Human CA9, His Avi Tag at 0.5 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Anti-CA9 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA. (QC Test) |
| Description | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | Q16790 |
| Amino Acid | Gln38-Asp414 |
| Construction | Gln38-Asp414 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE, > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 50mM Tris, 150mM NaCl (pH 7.5). |
| Synonyms | RCC-associated protein G250, RCC, P54/58N, MN, G250, Carbonic Anhydrase IX, Carbonate dehydratase IX, CA-IX, CA9 |
| Research Background | Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA9 is a transmembrane enzyme expressed primarily in carcinoma cells. It is one of the best markers for hypoxia and for RCC. Appears to be a novel specific biomarker for a cervical neoplasia. |
| Molecular Weight | 43.7 kDa (reducing condition), 52-65 kDa (due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated chemical structure | Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated molecular weight
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