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TargetMol | Compound Library

Anti-Cardiovascular Disease Compound Library

Catalog No. L5400

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1793 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5400

Anti-Cardiovascular Disease Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1793 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Supporting Files | TargetMol Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (60.2 MB)

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Adrenergic Receptor
Apoptosis
Calcium Channel
PDE
Autophagy
VEGFR
Endogenous Metabolite
COX
Sodium Channel
Potassium Channel
NF-κB
Antibacterial
5-HT Receptor
TNF
AChR
ROS
RAAS
PDGFR
Dopamine Receptor
Parasite
Angiotensin-converting Enzyme (ACE)
IL Receptor
FGFR
p38 MAPK
c-Kit
Interleukin
PARP
Histone Acetyltransferase
Histamine Receptor
FLT
PPAR
ERK
Reactive Oxygen Species
Akt
Drug Metabolite
CDK
NO Synthase
Cytochromes P450
HMG-CoA Reductase
EGFR
PKC
Adenosine Receptor
Factor Xa
DNA/RNA Synthesis
Antifungal
BACE
JAK
Epigenetic Reader Domain
PI3K
Antioxidant
Prostaglandin Receptor
Antibiotic
Carbonic Anhydrase
Caspase
IGF-1R
Influenza Virus
ATPase
Src
Ferroptosis
c-Met/HGFR
Mitophagy
c-RET
Thrombin
HIV Protease
JNK
Beta-Secretase
PKA
TRP/TRPV Channel
Norepinephrine
SARS-CoV
Nrf2
Phospholipase
P2Y Receptor
Glucocorticoid Receptor
STAT
NOD-like Receptor (NLR)
GSK-3
Wnt/beta-catenin
Cholinesterase (ChE)
CaMK
P-gp
Beta Amyloid
HDAC
GABA Receptor
Proteasome
Integrin
iGluR
Mitochondrial Metabolism
Lipoxygenase
Virus Protease
Raf
Guanylate cyclase
AMPK
Anti-infection
MRP
Bcr-Abl
c-Fms
MEK
Monoamine Oxidase
Proton pump
Dehydrogenase
Tyrosine Kinases
Serine Protease
Serotonin Transporter
ROCK
LDLR
NMDAR
Aurora Kinase
Acetyl-CoA Carboxylase
Hydroxylase
Tyrosinase
NADPH
Tie-2
Glutathione Peroxidase
MAO
Topoisomerase
MMP
Bcl-2 Family
IκB/IKK
NOD
Microtubule Associated
Chloride channel
Amino Acids and Derivatives
Na+/Ca2+ Exchanger
CETP
PERK
Serine/threonin kinase
Nucleoside Antimetabolite/Analog
Liver X Receptor
FXR
LDL
P2X Receptor
Opioid Receptor
Fatty Acid Synthase
HSV
GluR
mTOR
TGF-beta/Smad
Acyltransferase
TLR
Trk receptor
TAM Receptor
FAK
HIF/HIF Prolyl-Hydroxylase
GPCR
NOS
Myosin
DPP-4
Chk
Epoxide Hydrolase
cAMP
PGE Synthase
MAPK
HSP
Sirtuin
Ephrin Receptor
RSV
Neprilysin
HIF
Ras
Sigma receptor
Protease-activated Receptor
Imidazoline Receptor
p53
Thyroid hormone receptor(THR)
Histone Methyltransferase
Arginase
DNA Alkylator/Crosslinker
Reductase
Estrogen Receptor/ERR
Leukotriene Receptor
CSF-1R
Immunology/Inflammation related
RIP kinase
UGT
Na-K-Cl cotransporter
HCN Channel
Endothelin Receptor
Androgen Receptor
Lipid
transporter
PAI-1
ALK
Reverse Transcriptase
PDK
MDM-2/p53
Platelet aggregation
Syk
NADPH-oxidase
S6 Kinase
Vitamin
MTP
Adenylyl Cyclase
Transferase
Monocarboxylate transporter
DHFR
ROR
Estrogen/progestogen Receptor
Factor VIIa
LPL Receptor
LTR
IFNAR
Histone Demethylase
Necroptosis
Phosphatase
Rho
Antifolate
PYK2
Amylase
Prolyl Endopeptidase (PREP)
Annexin A
Gamma-secretase
ABC Transporter
Glucosidase
Antifection
Monoamine Transporter
DNA Alkylation
FAAH
CCR
Xanthine Oxidase
Thrombopoietin Receptor
glycosidase
DNA
OXPHOS
Aminopeptidase
GPCR19
ASK
Casein Kinase
FKBP
SGK
Gap Junction Protein
DNA Methyltransferase
IRAK
AhR
CFTR
MLK
NPC1L1
DNA-PK
HCV Protease
DprE1
YAP
Lipase
MIF
TOPK
Progesterone Receptor
OCT
N-Acetylglucosaminyltransferase
CaSR
HBV
VDAC
Cell Cycle Arrest
Cysteine Protease
Neurotensin Receptor
Glucokinase
Aryl Hydrocarbon Receptor
IDO
IAP
IRE1
Photosystem (PS)
FLAP
Adiponectin Receptor
PAFR
GRK
Arp2/3 Complex
DNA gyrase
GlyT
Anion Exchanger
Isocitrate Dehydrogenase (IDH)
Hedgehog/Smoothened
Vasopressin Receptor
ACK1
CXCR
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
ATP Citrate Lyase
BCRP
OAT
Antiviral
STING
LRRK2
AIM2
Decarboxylase
GST
Retinoid Receptor
Kras
Aromatase
CRISPR/Cas9
RXFP receptor
PLK
Cuproptosis
Cannabinoid Receptor
Discoidin Domain Receptor (DDR)
Tight Junction Protein
p97
ROS Kinase
HER
PKM
S1P Receptor
ADC Cytotoxin
Sodium-dependent phosphate transporter
BTK
PGC-1α

Keywords

Target-based screeningSmall molecule compoundsPhenotypic screeningHypertensionHigh-throughput screeningHeart failureCoronary heart diseaseCompound libraryCardiovascular screening libraryCardiovascular researchCardiovascular lead compoundsCardiovascular drug discoveryCardiovascular disorderCardiovascular diseaseAtherosclerosisAntiCardiovascular Disease Compound LibraryAnti Cardiovascular Disease Compound Library
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