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Tetrahydroberberine

Catalog No. T2874 CAS 522-97-4

Synonyms: Tetrahydroberberine THB, Canadine

Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.

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Tetrahydroberberine, CAS 522-97-4

Pack Size	Availability	Price/USD
5 mg	In stock	$ 40.00
10 mg	In stock	$ 57.00
25 mg	In stock	$ 94.00
50 mg	In stock	$ 139.00
100 mg	In stock	$ 198.00
500 mg	In stock	$ 513.00
1 mL * 10 mM (in DMSO)	In stock	$ 52.00

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Purity: 99.89%

Purity: 96.65%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
Targets&IC50	5-HT1A:5.38(pKi), D2 receptor:6.08(pKi)
Source	Natural Products > Ranunculaceae > Coptis

Synonyms	Tetrahydroberberine THB, Canadine
Molecular Weight	339.39
Formula	C20H21NO4
CAS No.	522-97-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.73 mg/mL (10.99 mM)

References and Literature

1. Pingali S, et al. Acta Crystallogr C Struct Chem. 2015 Apr;71(Pt 4):262-5.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library GPCR Compound Library Antiparasitic Natural Product Library Natural Product Library Alkaloid Natural Product Library RO5 Drug-like Natural Product Library NO PAINS Compound Library Endocrinology-Hormone Compound Library Chinese Pharmacopoeia Natural Product Library Traditional Chinese Medicine Monomer Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tetrahydroberberine 522-97-4 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor inhibit Inhibitor Tetrahydroberberine THB Canadine inhibitor

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