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Tectoridin

Name: Tectoridin
Brand: TargetMol
SKU: T3665
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3665Cas No. 611-40-5

Alias Shekanin

Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC : 1.4-15.5 μM).

Tectoridin

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Purity: 99.48%

Catalog No. T3665Alias ShekaninCas No. 611-40-5

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$37	In Stock	In Stock
10 mg	$50	In Stock	In Stock
25 mg	$78	In Stock	In Stock
50 mg	$113	In Stock	In Stock
100 mg	$163	In Stock	In Stock
200 mg	$239	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$44	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.48%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Tectoridin AI Summary

Tectoridin shows no inhibition of cow milk xanthine oxidase at a concentration of 50 µg/mL. It exhibits estrogenic activity in human MCF7 and T47D cells: in MCF7 cells, it is active at 0.02 µM (equivalent to 10 pM estradiol) and at 0.08 µM (equivalent to 100 pM estradiol); in T47D cells, it exhibits activity at 0.2 µM (equivalent to 10 pM estradiol). Additionally, Tectoridin inhibits beta-glucuronidase of unknown origin with an IC50 value of 300 µg/mL..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC : 1.4-15.5 μM).
Synonyms	Shekanin

Chemical Properties

Molecular Weight	462.40
Formula	C₂₂H₂₂O₁₁
Cas No.	611-40-5
Smiles	COc1c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc2occ(-c3ccc(O)cc3)c(=O)c2c1O
Relative Density.	1.609 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (540.66 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2.00 mg/mL (4.33 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1626 mL	10.8131 mL	21.6263 mL	108.1315 mL
5 mM	0.4325 mL	2.1626 mL	4.3253 mL	21.6263 mL
10 mM	0.2163 mL	1.0813 mL	2.1626 mL	10.8131 mL
20 mM	0.1081 mL	0.5407 mL	1.0813 mL	5.4066 mL
50 mM	0.0433 mL	0.2163 mL	0.4325 mL	2.1626 mL
100 mM	0.0216 mL	0.1081 mL	0.2163 mL	1.0813 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc