Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
2 mg | In stock | $ 54.00 | |
5 mg | In stock | $ 88.00 | |
10 mg | In stock | $ 139.00 | |
25 mg | In stock | $ 245.00 | |
50 mg | In stock | $ 393.00 | |
100 mg | In stock | $ 585.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 108.00 |
Description | TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM). |
Targets&IC50 | M1R:520 nM (EC50) |
In vivo | In rats, TAK-071(0.3 mg/kg) increase hippocampal inositol monophosphate production through M1R activation and improved DB00747 -induced cognitive deficits, TAK-071(10 mg/kg) also induce diarrhea . |
Molecular Weight | 421.46 |
Formula | C24H24FN3O3 |
CAS No. | 1820812-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 134 mg/mL(317.94 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TAK-071 1820812-16-5 Neuroscience AChR mAChR inhibit Muscarinic acetylcholine receptor TAK 071 TAK071 Inhibitor inhibitor