Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 313.00 | |
5 mg | In stock | $ 663.00 | |
10 mg | In stock | $ 995.00 | |
25 mg | In stock | $ 1,470.00 | |
50 mg | In stock | $ 1,990.00 | |
100 mg | In stock | $ 2,680.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 763.00 |
Description | Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA). |
In vitro | Treatment of Sanguisorbigenin with sub-MIC concentrations (1.56-6.25 μg/mL) significantly inhibited the expression of blaR1, mecA, and blaZ in MRSA dose-dependently. The gene expression of mecA is remarkably reduced after the treatment of Sanguisorbigenin. The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL[1]. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decreasing PBP2a expression[1]. |
Source |
Synonyms | Tomentosolic acid, 3β-Hydroxyurs-12,19-dien-28-oic acid, 19-Dehydroursolic acid, Ursa-12,19-dien-28-oic acid |
Molecular Weight | 454.68 |
Formula | C30H46O3 |
CAS No. | 6812-98-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (127.48 mM)
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Sanguisorbigenin 6812-98-2 Microbiology/Virology Antibacterial Tomentosolic acid PBP2a mecA Bacterial 3β-Hydroxyurs-12,19-dien-28-oic acid 19-Dehydroursolic acid Ursa-12,19-dien-28-oic acid 3b-Hydroxyurs-12,19-dien-28-oic acid MRSA inhibit Inhibitor 3beta-Hydroxyurs-12,19-dien-28-oic acid antibacterial inhibitor