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Salmeterol

Name: Salmeterol
Brand: TargetMol
SKU: T12829
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12829Cas No. 89365-50-4

Alias GR33343X

Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.

Salmeterol

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Purity: 99.9%

Catalog No. T12829Alias GR33343XCas No. 89365-50-4

Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.

Pack Size	Price	Availability
5 mg	$50	In Stock
10 mg	$80	In Stock
25 mg	$156	In Stock
50 mg	$288	In Stock
1 mL x 10 mM (in DMSO)	$70	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.9%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Salmeterol (GR33343X) is a long-acting agonist of beta2-adrenergic receptor (beta 2AR) used for treatment ofasthma.
Targets&IC50	β1-adrenoceptor:6.1 (pEC50), β3-adrenoceptor:5.9 (pEC50), β2-adrenoceptor:9.6 (pEC50)
Synonyms	GR33343X

Chemical Properties

Molecular Weight	415.57
Formula	C₂₅H₃₇NO₄
Cas No.	89365-50-4
Smiles	OCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc1ccccc1
Relative Density.	1.112 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (240.63 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (9.63 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4063 mL	12.0317 mL	24.0633 mL	120.3167 mL
5 mM	0.4813 mL	2.4063 mL	4.8127 mL	24.0633 mL
10 mM	0.2406 mL	1.2032 mL	2.4063 mL	12.0317 mL
20 mM	0.1203 mL	0.6016 mL	1.2032 mL	6.0158 mL
50 mM	0.0481 mL	0.2406 mL	0.4813 mL	2.4063 mL
100 mM	0.0241 mL	0.1203 mL	0.2406 mL	1.2032 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc