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S-(+)-Ketoprofen

Catalog No. T0839L   CAS 22161-81-5
Synonyms: RP-19583, Dexketoprofen, (S)-(+)-Ketoprofen, (S)-Ketoprofen

S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, S-(+)-Ketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action.S-(+)-Ketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as S-(+)-Ketoprofen trometamol, as a prescription-only drug and in Latin America as Miracox, produced by Stein in Costa Rica. In Italy it is available as an over the counter-drug under the tradename Enantyum. In Lithuania it is available as over the counter-drug uder tradename Dolmen.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
S-(+)-Ketoprofen Chemical Structure
S-(+)-Ketoprofen, CAS 22161-81-5
Pack Size Availability Price/USD Quantity
50 mg In stock $ 33.00
100 mg In stock $ 47.00
200 mg In stock $ 60.00
500 mg In stock $ 95.00
1 mL * 10 mM (in DMSO) In stock $ 39.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, S-(+)-Ketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action.S-(+)-Ketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as S-(+)-Ketoprofen trometamol, as a prescription-only drug and in Latin America as Miracox, produced by Stein in Costa Rica. In Italy it is available as an over the counter-drug under the tradename Enantyum. In Lithuania it is available as over the counter-drug uder tradename Dolmen.
Targets&IC50 COX-2:27 nM, COX-1:1.9 nM
Synonyms RP-19583, Dexketoprofen, (S)-(+)-Ketoprofen, (S)-Ketoprofen
Molecular Weight 254.28
Formula C16H14O3
CAS No. 22161-81-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (491.58 mM)

TargetMolReferences and Literature

1. Pelligand L, et al. J Vet Pharmacol Ther. 2014 Aug;37(4):354-66.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Neuronal Signaling Compound Library Anti-Colorectal Cancer Compound Library Anti-COVID-19 Compound Library Anti-Fibrosis Compound Library Clinical Compound Library

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Keywords

S-(+)-Ketoprofen 22161-81-5 Immunology/Inflammation Neuroscience COX RP-19583 Dexketoprofen Ketoprofen RP 19583 (S)-(+)-Ketoprofen S-Ketoprofen Inhibitor (S)-Ketoprofen S(+)Ketoprofen S (+) Ketoprofen inhibit RP19583 Cyclooxygenase inhibitor

 

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