Powder: -20°C for 3 years | In solvent: -80°C for 2 years
RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 133.00 | |
5 mg | In stock | $ 328.00 | |
10 mg | In stock | $ 555.00 | |
25 mg | In stock | $ 827.00 | |
50 mg | In stock | $ 1,140.00 | |
100 mg | In stock | $ 1,540.00 | |
200 mg | In stock | $ 1,990.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 365.00 |
Description | RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants. |
Targets&IC50 | PARP5b:10 μM (IC50), PARP11:1 μM (IC50), PARP6:4 μM (IC50), PARP14:<3 nM (IC50), PARP12:5 μM (IC50), PARP16:6 μM (IC50), PARP15:3 μM (IC50), PARP5a:8 μM (IC50), PARP10:1 μM (IC50), PARP7:4 μM (IC50), PARP4:10 μM (IC50), PARP8:20 μM (IC50) |
Molecular Weight | 378.46 |
Formula | C19H23FN2O3S |
CAS No. | 2360851-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
DMSO: 12 mg/mL (31.71 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RBN012759 2360851-29-0 Chromatin/Epigenetic DNA Damage/DNA Repair PARP poly ADP ribose polymerase pro-tumor cancer PARP14 macrophage RBN 012759 Inhibitor inflammatory inhibit RBN-012759 inhibitor