Powder: -20°C for 3 years | In solvent: -80°C for 1 year
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 87.00 | |
10 mg | In stock | $ 157.00 | |
25 mg | In stock | $ 357.00 | |
50 mg | In stock | $ 538.00 | |
100 mg | In stock | $ 778.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 109.00 |
Description | QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells. |
Targets&IC50 | ARFGAP1:1.5 µM (EC50) |
Synonyms | QS 11 |
Molecular Weight | 567.68 |
Formula | C36H33N5O2 |
CAS No. | 944328-88-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 100 mM
DMSO: 100 mM
You can also refer to dose conversion for different animals. More
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QS11 944328-88-5 GPCR/G Protein GTPase synergistic Wnt regenerative agonist signaling factors Inhibitor inhibit ADP-ribosylation QS 11 QS-11 inhibitor