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Catalog No. T16682   CAS 158364-59-1
Synonyms: BY-841

Pumaprazole is an antagonist of a reversible <a href="/target/Proton_pump" style="display: inline; color: #c13a36">Proton pump</a>.

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Pumaprazole, CAS 158364-59-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 347.00
5 mg In stock $ 896.00
10 mg In stock $ 1,427.00
25 mg In stock $ 2,137.00
1 mL * 10 mM (in DMSO) In stock $ 997.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Pumaprazole is an antagonist of a reversible proton pump.
In vivo Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1].
Synonyms BY-841
Molecular Weight 338.4
Formula C19H22N4O2
CAS No. 158364-59-1


Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 55 mg/ml (162.53 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kromer W, et al. Animal pharmacology of reversible antagonism of the gastric acid pump, compared to standard antisecretory principles. Pharmacology. 2000 May;60(4):179-87.

Related compound libraries

This product is contained In the following compound libraries:
ReFRAME Related Library Bioactive Compounds Library Max Inhibitor Library Bioactive Compound Library Anti-Cancer Compound Library

Related Products

Related compounds with same targets
Vonoprazan Bafilomycin A1 Tenatoprazole Bamaquimast Omeprazole sulfide Vonoprazan Fumarate Pumaprazole 5-Hydroxylansoprazole

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Pumaprazole 158364-59-1 Membrane transporter/Ion channel Proton pump inhibit BY-841 Proton Pump BY 841 BY841 Inhibitor inhibitor