Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Pumaprazole is an antagonist of a reversible <a href="/target/Proton_pump" style="display: inline; color: #c13a36">Proton pump</a>.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 347.00 | |
5 mg | In stock | $ 896.00 | |
10 mg | In stock | $ 1,427.00 | |
25 mg | In stock | $ 2,137.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 997.00 |
Description | Pumaprazole is an antagonist of a reversible proton pump. |
In vivo | Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1]. |
Synonyms | BY-841 |
Molecular Weight | 338.4 |
Formula | C19H22N4O2 |
CAS No. | 158364-59-1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 55 mg/ml (162.53 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Pumaprazole 158364-59-1 Membrane transporter/Ion channel Proton pump inhibit BY-841 Proton Pump BY 841 BY841 Inhibitor inhibitor