Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 63.00 | |
10 mg | In stock | $ 81.00 | |
25 mg | In stock | $ 163.00 | |
50 mg | In stock | $ 297.00 | |
100 mg | In stock | $ 468.00 |
Description | Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity. |
Targets&IC50 | Akt:4.7 μM |
Kinase Assay | Akt kinase assay: MM.1S cells are cultured in the presence or absence of perifosine (5 μM, 6 hours) and then stimulated with IL-6 (20 ng/mL, 10 minutes). In vitro akt kinase assay is then carried out using the Akt Kinase Assay Kit. |
Cell Research | Cells are incubated in the medium with 10% FCS for 48 hours with indicated concentration of Periosine. Cell viability is determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. (Cell Proliferation Kit I; Roche). The absorbance at 590 nm is recorded using the 96-well plate reader.(Only for Reference) |
Synonyms | NSC 639966, D21266, KRX-0401 |
Molecular Weight | 461.66 |
Formula | C25H52NO4P |
CAS No. | 157716-52-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
H2O: 10 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Perifosine 157716-52-4 Apoptosis Autophagy Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt NSC 639966 Protein kinase B Inhibitor NSC639966 D21266 KRX 0401 KRX-0401 KRX0401 inhibit PKB D 21266 NSC-639966 D-21266 inhibitor