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OR-1896

OR-1896
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Purity:99.51%
ee:98.65%

OR-1896

Catalog No. T12315Cas No. 220246-81-1
OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.OR-1896 can be used to study heart failure and vascular dysfunction. OR-1896 can be used to study heart failure and vascular dysfunction.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$93In Stock
2 mg$137In Stock
5 mg$228In Stock
10 mg$413In Stock
25 mg$892In Stock
50 mg$1,220In Stock
100 mg$1,650In Stock
1 mL x 10 mM (in DMSO)$253In Stock
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Product Introduction

Bioactivity
Description
OR-1896 is the active metabolite of Levosimendan, a highly specific phosphodiesterase (PDE III) inhibitor, a vasodilator with partial anti-inflammatory properties that produces vasodilation in different types of blood vessels through activation of ATP-sensitive (KATP) and other potassium channels.OR-1896 can be used to study heart failure and vascular dysfunction. OR-1896 can be used to study heart failure and vascular dysfunction.
In vitro
OR-1896 can achieve vasodilation by activating ATP-sensitive potassium channels in smooth muscle cells[1].
Chemical Properties
Molecular Weight245.28
FormulaC13H15N3O2
Cas No.220246-81-1
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (203.85 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0770 mL20.3849 mL40.7697 mL203.8487 mL
5 mM0.8154 mL4.0770 mL8.1539 mL40.7697 mL
10 mM0.4077 mL2.0385 mL4.0770 mL20.3849 mL
20 mM0.2038 mL1.0192 mL2.0385 mL10.1924 mL
50 mM0.0815 mL0.4077 mL0.8154 mL4.0770 mL
100 mM0.0408 mL0.2038 mL0.4077 mL2.0385 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg, each TargetMol | Animal experiments animal weighs 20 g, and the dosage volume is 100 μL. A total of TargetMol | Animal experiments 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify.
1 Enter information below:
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