Powder: -20°C for 3 years
In solvent: -80°C for 2 years
OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator.
Description | OR-1896 is an active long-lived Levosimendan metabolite, is a highly selective inhibitor of phosphodiesterase (PDE) III isoformand a powerful vasodilator. |
In vitro | OR-1896 evokes prominent vasodilatory responses, activation of ATP-sensitive sarcolemmal K+ channels of smooth muscle cells appears as a powerful vasodilator mechanism.?Additionally, activation of ATP-sensitive K+ channels in the mitochondria potentially extends the range of cellular actions towards the modulation of mitochondrial ATP production and implicates a pharmacological mechanism for cardioprotection[1]. |
Molecular Weight | 245.28 |
Formula | C13H15N3O2 |
CAS No. | 220246-81-1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 62.5 mg/mL (254.81 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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OR-1896 220246-81-1 Metabolism PDE OR 1896 OR1896 Inhibitor inhibitor inhibit