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Nikethamide

Name: Nikethamide
Brand: TargetMol
SKU: T0048
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0048Cas No. 59-26-7

Alias N,N-Diethylnicotinamide, Corvotone, Corvin, Anacardone

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now thought to be of no value for such purposes, and may be dangerous.

Nikethamide

🥰Excellent

Purity: 99.42%

Catalog No. T0048Alias N,N-Diethylnicotinamide, Corvotone, Corvin, AnacardoneCas No. 59-26-7

Pack Size	Price	Availability
500 mg	$40	In Stock
1 g	$50	In Stock
5 g	$113	In Stock
10 g	$166	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Purity:99.42%

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COA LCMS HNMR HPLC

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Product Introduction

Bioactivity

Description	Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now thought to be of no value for such purposes, and may be dangerous.
Alias	N,N-Diethylnicotinamide, Corvotone, Corvin, Anacardone

Chemical Properties

Molecular Weight	178.23
Formula	C₁₀H₁₄N₂O
Cas No.	59-26-7
Smiles	CCN(CC)C(=O)c1cccnc1
Relative Density.	1.06g/mLat 25°C(lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (252.48 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.6107 mL	28.0536 mL	56.1073 mL	280.5364 mL
5 mM	1.1221 mL	5.6107 mL	11.2215 mL	56.1073 mL
10 mM	0.5611 mL	2.8054 mL	5.6107 mL	28.0536 mL
20 mM	0.2805 mL	1.4027 mL	2.8054 mL	14.0268 mL
50 mM	0.1122 mL	0.5611 mL	1.1221 mL	5.6107 mL
100 mM	0.0561 mL	0.2805 mL	0.5611 mL	2.8054 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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