Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MRT-81 inhibits human and rodent smoothened Smo receptors effectively with an IC50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 86.00 | |
2 mg | In stock | $ 127.00 | |
5 mg | In stock | $ 213.00 | |
10 mg | In stock | $ 343.00 | |
25 mg | In stock | $ 583.00 | |
50 mg | In stock | $ 833.00 | |
100 mg | In stock | $ 1,150.00 | |
500 mg | In stock | $ 2,290.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 262.00 |
Description | MRT-81 inhibits human and rodent smoothened Smo receptors effectively with an IC50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1]. |
Targets&IC50 | Smo receptor (Shh-light2 cells):41 nM (IC50) |
In vitro | MRT-81 inhibits the differentiation of the mesenchymal pluripotent C3H10T1/2 cells into alkaline phosphatase positive osteoblasts induced by the Smo agonist SAG with 0.1 μM, with an IC50 value of 64 nM[1]. |
Molecular Weight | 555.64 |
Formula | C31H29N3O5S |
CAS No. | 1263132-08-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (89.98 mM)
You can also refer to dose conversion for different animals. More
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MRT-81 1263132-08-6 Others Smo Smoothened human C3H10T1/2 cells inhibit Shh-light2 cells rodent BODIPY-cyclopamine MRT81 rat granule cell precursors Inhibitor MRT 81 inhibitor