Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 40.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 90.00 | |
25 mg | In stock | $ 158.00 | |
50 mg | In stock | $ 265.00 | |
100 mg | In stock | $ 398.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 68.00 |
Description | ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels. |
Targets&IC50 | Nav1.7:19 nM |
Synonyms | 2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl |
Molecular Weight | 449.55 |
Formula | C23H19N3O3S2 |
CAS No. | 313254-51-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 44 mg/mL (97.88 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ICA-121431 313254-51-2 Membrane transporter/Ion channel Sodium Channel Nav Na channels ICA 121431 inhibitor TTX-resistant channel Na+ channels 2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl inhibit ICA121431