Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
5 mg | In stock | $ 85.00 | |
10 mg | In stock | $ 130.00 | |
25 mg | In stock | $ 228.00 | |
50 mg | In stock | $ 369.00 | |
100 mg | In stock | $ 549.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2). |
In vitro | In the presence of an equal concentration of cAMP, HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM. |
Molecular Weight | 339.45 |
Formula | C19H21N3OS |
CAS No. | 1383539-73-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (73.65 mM)
You can also refer to dose conversion for different animals. More
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HJC0197 1383539-73-8 GPCR/G Protein MAPK cAMP Ras cAMP-signaling activation GEF cellular inhibit HJC-0197 phosphorylation processes HJC 0197 Inhibitor inhibitor