keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G3335 Acetate was discovered to be a novel PPARgamma antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 75.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 192.00 | |
100 mg | In stock | $ 287.00 | |
200 mg | In stock | $ 431.00 | |
500 mg | In stock | $ 713.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 72.00 |
Description | G3335 Acetate was discovered to be a novel PPARgamma antagonist. |
Targets&IC50 | PPARγ:8.34 μM(kd), PPARγ:8.67 μM(kd) |
In vitro | G3335 exhibits a highly specific binding affinity against PPARgamma (K(D) = 8.34 microM) and is able to block rosiglitazone, a potent PPARgamma agonist, in the stimulation of the interaction between the PPARgamma ligand-binding domain (LBD) and RXRalpha-LBD. Yeast two-hybrid assays demonstrated that G3335 exhibits strong antagonistic activity (IC50 = 8.67 microM) in perturbing rosiglitazone in the promotion of the PPARgamma-LBD-CBP interaction. |
Synonyms | G3335 Acetate (36099-95-3 free base) |
Molecular Weight | 393.39 |
Formula | C18H23N3O7 |
CAS No. | T21598L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (139.81 mM)
You can also refer to dose conversion for different animals. More
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G3335 Acetate T21598L DNA Damage/DNA Repair Metabolism PPAR 36099-95-3 36099-95-3 free base G3335 Acetate (36099-95-3 free base) G 3335 Acetate G-3335 Acetate inhibitor inhibit