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Pack Size | Price | Availability | Quantity |
---|---|---|---|
200 mg | $33 | In Stock | |
500 mg | $52 | In Stock | |
1 g | $81 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Dirithromycin (LY237216) is a macrolide glycopeptide antibiotic. It is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections. |
In vivo | At therapeutic concentrations, Dirithromycin enhances the production of IL1β in cells stimulated by lipopolysaccharides, with increases of +37% and +28% at 1 μg/mL. At supra-therapeutic concentrations, Dirithromycin inhibits IL1β through the inhibition of protein kinase C; the concentration of Dirithromycin when 50% inhibition is achieved is 378 mg/mL, while for Spiramycin it is 234 mg/mL. |
Alias | Dirithromycinum, ASE 136, LY237216, Diritromicina, Dirithromycine |
Molecular Weight | 835.07 |
Formula | C42H78N2O14 |
Cas No. | 62013-04-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 1 mg/mL, Sonication is recommended. ![]() Ethanol: 93 mg/mL (111.4 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol
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