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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5164 | Cabozantinib hydrochloride | XL184 , Cabozantinib hydrochloride (849217-68-1(free base)) , BMS-907351 | c-Kit , ROR , TAM Receptor , c-Met/HGFR , FLT , VEGFR |
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM). |