Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. An example of a PROTAC BTK degrader incorporating Lenalidomide-OH is SJF620.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 42.00 | |
25 mg | In stock | $ 68.00 | |
50 mg | In stock | $ 98.00 | |
100 mg | In stock | $ 147.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 162.00 |
Description | Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. An example of a PROTAC BTK degrader incorporating Lenalidomide-OH is SJF620. |
In vitro | Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs which are the inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. |
Molecular Weight | 260.25 |
Formula | C13H12N2O4 |
CAS No. | 1416990-08-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (42.27 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Lenalidomide-OH 1416990-08-3 PROTAC Ligand for E3 Ligase LenalidomideOH inhibit E3 ligase-recruiting Moiety Inhibitor Ligands for E3 Ligase Lenalidomide OH inhibitor